Jockey Calvin Borel, winner of the Kentucky Derby three of the past four years, will compete for the Run for the Roses again this year.
Borel was given the mount on Twice the Appeal, according to Churchill Downs.
Twice the Appeal earned his shot at the 137th Kentucky Derby by winning the $800,000 Sunland Derby last month as a 25-1 shot with Christian Santiago-Reyes aboard.
"It's not as easy as everybody thinks it is. If you win the Derby today, but tomorrow is another day. You got to jump right into it. You really get no rest, and it's very tough. People don't realize it."
Trainer Jeff Bonde told the Daily Racing Form that the horse's ownership group voted to go with Borel.
Twice the Appeal is scheduled to go out for his final Derby workout on Friday morning at Churchill Downs, with Borel aboard.
Borel won the Derby in 2007 aboard Street Sense, in 2009 with Mine That Bird and last year on Super Saver.